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Title: Impact of enhancin genes on potency of LdNPV in gypsy moth
Author: Hoover, Kelli; McNeil, Jim; Gendron, Alyssa; Slavicek, James.
Publication: In: McManus, Katherine A; Gottschalk, Kurt W., eds. 2010. Proceedings. 21st U.S. Department of Agriculture interagency research forum on invasive species 2010; 2010 January 12-15; Annapolis, MD. Gen. Tech. Rep. NRS-P-75. Newtown Square, PA: U.S. Department of Agriculture, Forest Service, Northern Research Station: 93.
Abstract: Lymantria dispar nucleopolyhedrovirus (LdNPV) contains two enhancin genes (E1 and E2) encoding proteases that degrade key peritrophic matrix (PM) proteins, thereby promoting infection and mortality by the virus. In a previous study, gypsy moth larvae inoculated with LdNPV in which both E1 and E2 were deleted (double deletion virus) resulted in a non-additive decrease in viral potency compared to potencies of viruses with only 1 of the 2 genes deleted.
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